Thisrabbitpolyclonalantibodywasgeneratedagainstrecombinanthumanironregulatoryprotein1(IRP1)andrecognizeshumanandmouseIRP1.
Highlights:
- Reactswithhumanandmouse,full-lengthIRP1
- SuitableforWesternBlotandImmunoprecipitationapplications
IRP1standsfor“ironregulatoryprotein1”.ItisencodedbytheACO1gene(aconitase1).IRP1isasolubleproteinandanironsensor.Whencellularironlevelsarehigh,thisproteinbindstoa4Fe-4Sclusterandfunctionsasanaconitase.Aconitasesareiron-sulfurproteinsthatfunctiontocatalyzetheconversionofcitratetoisocitrate.
FromthelaboratoryofKostasPantopoulos,PhD,McGillUniversity.
| ProductType: | Antibody |
| AccessionID: | P21399 |
| Antigen: | HumanIRP1 |
| MolecularWeight: | 100kDa |
| Clonality: | Polyclonal |
| Reactivity: | HumanandMouse |
| Immunogen: | RecombinanthumanIRP1 |
| SpeciesImmunized: | Rabbit |
| Epitope: | FulllengthIRP1 |
| PurificationMethod: | Serum |
| Buffer: | Serumwith0.05%sodiumazide |
| TestedApplications: | WB(1:2000)andIP |
| Storage: | -80C |
| Shipped: | DryIce |
- FillebeenC,ChahineD,CaltagironeA,SegalP,PantopoulosK.AphosphomimeticmutationatSer-138rendersironregulatoryprotein1sensitivetoiron-dependentdegradation.MolCellBiol.2003Oct;23(19):6973-81.
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