请使用支持JavaScript的浏览器!
主营:cell lines, antibodies, small molecules, dyes ...
banner
当前位置: 首页 > 产品中心 > > Kerafast/Anti-ADAM15 (mouse), Cytoplasmic Domain Antibody/EHS005/100uL

Kerafast/Anti-ADAM15 (mouse), Cytoplasmic Domain Antibody/EHS005/100uL

Kerafast/Anti-ADAM15 (mouse), Cytoplasmic Domain Antibody/EHS005/100uL
  • Kerafast/Anti-ADAM15 (mouse), Cytoplasmic Domain Antibody/EHS005/100uL
商品介绍

ThisrabbitIgGpolyclonalantibodywasgeneratedagainsttheGST-ADAM15-cytoplasmictailandisspecificforthecytoplasmicdomainofmouseADAM15.

TheADAM(ADisintegrinAndMetalloproteaseDomain)familyisauniquegroupofproteinsthathastheABIlitytocleaveorshedextracellularportionsoftransmembraneproteins.Inaddition,ADAMsareinvolvedincell-cellandcell-matrixinteractions(e.g.,fertilization,muscledevelopmentandneurogenesis).

ADAM15(Metargidin)isamembrane-anchoredmetalloproteinasethathasbeenimplicatedinpathologicalneovascularizationandprostatecancermetastasis.

FromthelaboratoryofCarlP.Blobel,MD,PhD,HospitalforSpecialSurgery.

The InvestigatorPartofTheInvestigator"sAnnexeprogram.

Specifications
ProductType: Antibody
AccessionID: AF006196
Antigen: GST-ADAM15cytoplasmicdomain
MolecularWeight: ~100kDa
Isotype: IgG
Clonality: Polyclonal
Reactivity: Mouse
Immunogen: GST-cytocorrespondingtothecytoplasmicdomainofmouseADAM15
SpeciesImmunized: Rabbit
Epitope: Cytoplasmicdomain
PurificationMethod: Serum,notpurified
TestedApplications: WB(1:500)
Storage: -80C
Shipped: Dryice
Research
AntibodySpeciesReactivitySpecificity
ADAM9HumanCytoplasmicDomain
ADAM9MouseCytoplasmicDomain
ADAM12MouseCytoplasmicDomain
ADAM15HumanCytoplasmicDomain
ADAM15MouseCytoplasmicDomain
ADAM15HumanExtracellularDomain
ADAM15MouseDisintegrinDomain
ADAM17MouseCytoplasmicDomain
ADAM17MouseProdomain
ADAM19MouseCytoplasmicDomain
ADAM28MouseCytoplasmicDomain
ADAM28MouseExtracellularDomain
SNX9MouseCytoplasmicDomain
Data

WesternBlotAnalysis

WesternblotofreducedglycoproteinsfromtheindicatedtissueswereprobedwithADAM15cytoplasmicdomainantibody.

Adaptedfrom:LumL,etal.J.BiolChem.1998,273,26236-26247.

Provider
FromthelaboratoryofCarlP.Blobel,MD,PhD,HospitalforSpecialSurgery.
References
  1. LumL.;Reid,M.S.;Blobel,C.P.IntracellularmaturationofthemousemetalloproteasedisintegrinMDC15.J.BiolChem.1998,273,26236-26247.
  2. HoriuchiK,WeskampG,LumL,HammesHP,CaiH,BrodieTA,LudwigT,ChiusaroliR,BaronR,PreissnerKT,ManovaK,BlobelCP.PotentialroleforADAM15inpathologicalneovascularizationinmice.MolCellBiol.2003Aug;23(16):5614-24.
  3. MaretzkyT,YangG,OuerfelliO,OverallCM,WorpenbergS,HassiepenU,EderJ,BlobelCP.Characterizationofthecatalyticactivityofthemembrane-anchoredmetalloproteinaseADAM15incell-basedassays.BiochemJ.2009Apr28;420(1):105-13.
  4. MaretzkyT,LeGallSM,Worpenberg-PietrukS,EderJ,OverallCM,HuangXY,PoghosyanZ,EdwardsDR,BlobelCP.Srcstimulatesfibroblastgrowthfactorreceptor-2sheddingbyanADAM15splicevariantlinkedtobreastcancer.CancerRes.2009Jun1;69(11):4573-6.

Ifyoupublishresearchwiththisproduct,pleaseletusknowsowecanciteyourpaper.

品牌介绍

Kerafast是位于波士顿的试剂公司,其主要任务是为全球科学界提供特有的实验室研究工具。其产品组合包括细胞系,抗体,小分子,染料等,其中许多在其他地方不可用。自2011年成立以来,全球超过160家机构的研究人员通过Kerafast在线平台提供了创新试剂,在这个平台上,材料可以快速访问,无需通过传统的材料转移协议流程。

在Kerafast,可通过MTA共享的材料,如抗体,细胞系,化合物,病毒载体,质粒等。随着文书工作,延误和成本不断上升,MTA交换过程正在成为学术实验室的沉重负担,因为Kerafast计划可以快速有效地进行补救。

 

自营商城图标
厂家直采
全球直采模式 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔
在线客服
客服电话

4000-520-616

0512-67156496