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主营:cell lines, antibodies, small molecules, dyes ...
℡ 4000-520-616
℡ 4000-520-616
Kerafast/Anti-ABCD2 Antibody/EKY001/100uL
产品编号:EKY001
市  场 价:¥5000.00
场      地:美国(厂家直采)
产品分类: 抗体类>二抗>其他二抗>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$250.00
品      牌: Kerafast
公      司:Kerafast, Inc.
公司分类:
Kerafast/Anti-ABCD2 Antibody/EKY001/100uL
商品介绍

Thisrabbitpolyclonalantibodywasraisedagainstfusionproteinandrecognizeshuman,mouseandratATPBindingCassetteSubfamilyDMember2(ABCD2).

Highlights:

  • Reactswithhuman,mouseandratABCD2
  • SuitableforWesternBlotandImmunofluorescenceandImmuneElectronMicroscopyapplications

ABCD2isamemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintra-cellularmembranes.ABCgenesaredividedintosevendistinctsubfamiliesandthisproteinisamemberoftheALDsubfamily,whichisinvolvedinperoxisomalimportoffattyacidsand/orfattyacyl-CoAsintheorganelle.DiseasesassociatedwithABCD2includeAdrenoleukodystrophyandDemyelinatingDisease.

FromthelaboratoryofGregA.Graf,PhD,UniversityofKentucky.

Specifications
ProductType: Antibody
Antigen: ABCD2peptide
AccessionID: GeneID:26874
MolecularWeight: 78kDa
Clonality: Polyclonal
Reactivity: Mouse,RatandHuman
Immunogen: FusionPeptide
SpeciesImmunized: Rabbit
Epitope: Aa377-711
Buffer: 50%glycerol,50mMtris(pH7.4)and0.01%azide
TestedApplications: WB(1:2000),IF(1:200),IEM(1:50)
Storage: -80C
Shipped: DryIce
Data

ImmunofluorescenceMicroscopyandImmunoblotAnalysisofD2ProteininCulturedCells.


(A)CellsweretransfectedwithaplasmidcontainingaCDNAencodingmouseD2.CellswereprocessedforindirectimmunofluorescencemicroscopyusingthepolyclonalD2antibody.Inset:lysatesfromcellstransfectedwithcontrolplasmid(V)andD2wereanalyzedbySDS-PAGEandimmunoblotting.(B)TotalmembraneswerepreparedfromADIposecollectedfromwild-typeandD2-deficient(D2-/-)miceandanalyzedbyimmunoblottingwiththeD2antibody.

Provider
FromthelaboratoryofGregA.Graf,PhD,UniversityofKentucky.

References
  1. LiuJ,SabevaNS,BhatnagarS,LiXA,PujolA,GrafGA.ABCD2isabundantinadiposetissueandopposestheaccumulationofdietaryerucicacid(C22:1)infat.JLipidRes.2010Jan;51(1):162-8.
  2. LiuJ,LiangS,LiuX,BrownJA,NewmanKE,SunkaraM,MorrisAJ,BhatnagarS,LiX,PujolA,GrafGA.TheabsenceofABCD2sensitizesmicetodisruptionsinlipidmetabolismbydietaryerucicacid.JLipidRes.2012Jun;53(6):1071-9.
  3. LiuX,LiuJ,LesterJD,PijutSS,GrafGA.ABCD2identifiesasubclassofperoxisomesinmouseadiposetissue.BiochemBiophysResCommun.2015Jan2;456(1):129-34.

Ifyoupublishresearchwiththisproduct,pleaseletusknowsowecanciteyourpaper.

品牌介绍

Kerafast是位于波士顿的试剂公司,其主要任务是为全球科学界提供特有的实验室研究工具。其产品组合包括细胞系,抗体,小分子,染料等,其中许多在其他地方不可用。自2011年成立以来,全球超过160家机构的研究人员通过Kerafast在线平台提供了创新试剂,在这个平台上,材料可以快速访问,无需通过传统的材料转移协议流程。

在Kerafast,可通过MTA共享的材料,如抗体,细胞系,化合物,病毒载体,质粒等。随着文书工作,延误和成本不断上升,MTA交换过程正在成为学术实验室的沉重负担,因为Kerafast计划可以快速有效地进行补救。

 

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