Thisrabbitpolyclonalantibodywasraisedagainstfusionproteinandrecognizeshuman,mouseandratATPBindingCassetteSubfamilyDMember2(ABCD2).
Highlights:
ABCD2isamemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintra-cellularmembranes.ABCgenesaredividedintosevendistinctsubfamiliesandthisproteinisamemberoftheALDsubfamily,whichisinvolvedinperoxisomalimportoffattyacidsand/orfattyacyl-CoAsintheorganelle.DiseasesassociatedwithABCD2includeAdrenoleukodystrophyandDemyelinatingDisease.
FromthelaboratoryofGregA.Graf,PhD,UniversityofKentucky.
ProductType: | Antibody |
Antigen: | ABCD2peptide |
AccessionID: | GeneID:26874 |
MolecularWeight: | 78kDa |
Clonality: | Polyclonal |
Reactivity: | Mouse,RatandHuman |
Immunogen: | FusionPeptide |
SpeciesImmunized: | Rabbit |
Epitope: | Aa377-711 |
Buffer: | 50%glycerol,50mMtris(pH7.4)and0.01%azide |
TestedApplications: | WB(1:2000),IF(1:200),IEM(1:50) |
Storage: | -80C |
Shipped: | DryIce |
ImmunofluorescenceMicroscopyandImmunoblotAnalysisofD2ProteininCulturedCells.
(A)CellsweretransfectedwithaplasmidcontainingaCDNAencodingmouseD2.CellswereprocessedforindirectimmunofluorescencemicroscopyusingthepolyclonalD2antibody.Inset:lysatesfromcellstransfectedwithcontrolplasmid(V)andD2wereanalyzedbySDS-PAGEandimmunoblotting.(B)TotalmembraneswerepreparedfromADIposecollectedfromwild-typeandD2-deficient(D2-/-)miceandanalyzedbyimmunoblottingwiththeD2antibody.
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